Year: 2017
3/6 [elc]   ELC Seminar (Prof. Pekka Orponen)
Place : CELC Seminar Room
ELC C01 Seminar

Date: March 6th, 4:00 - 5:00
Place: ELC Seminar room (Tokyo Tech CIC, Tamachi, 4F)

Title: Algorithmic design of complex 3D DNA origami structures
Speaker: Pekka Orponen
         Aalto University, Computer Science

Abstract:
In a recent work (Nature 523:441-444, July 2015), we described a general
methodology and software pipeline for rendering 3D polyhedral mesh
designs in DNA. In this talk, I will first summarise the basic idea of
Paul Rothemund's DNA origami technique which also underlies our
approach, and then proceed to discuss the graph-theoretic concepts and
algorithmic ideas used in extending his technique from 2D patterns to 3D
wireframe mesh structures. The reliability and generality of the
approach is demonstrated by a number of electron microscopy images of
synthesised nanostructures, including a 50-nm rendering of the
widely-used Stanford Bunny model.

Host: Osamu Watanabe (watanabe@is.titech.ac.jp)


horiyama@al.ics.saitama-u.ac.jp